Cyril J Peter, PhD
- ASSISTANT PROFESSOR | Psychiatry
Dr. Peter is an Assistant Professor of Research in the Division of Psychiatric Epigenomics. For two years, Dr. Peter has been an integral part of Schahram Akbarian’s, MD, PhD, laboratory team, which recently came to Mount Sinai and is studying the epigenetic mechanisms of psychiatric disorders.
Dr. Peter’s research focuses on identifying and characterizing novel proteins and molecular interactions involved in chromatin remodeling and epigenetic regulation in human vertebrae and brain. His goal is to translate those findings and develop new chromatin modifying drugs that have therapeutic potential for neuropsychiatric diseases. In addition, he will contribute to grants and projects for the Center of Excellence, organize a monthly seminar on psychiatric epigenetics, and serve as a mentor to graduate and postdoctoral students.
Prior to joining Mount Sinai, Dr. Peter was an instructor at Brudnick Neuropsychiatric Research Institute at the University of Massachusetts Medical School. During his training, he identified a novel chromatin protein complex, which may play a key role in epigenetic mechanisms in the brain.
Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S. Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition. Neuron 2014 Nov; 84(5).
Mitchell A, Roussos P, Peter C, Tsankova N, Akbarian S. The future of neuroepigenetics in the human brain. Progress in molecular biology and translational science 2014; 128.
Houston I, Peter CJ, Mitchell A, Straubhaar J, Rogaev E, Akbarian S. Epigenetics in the human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013 Jan; 38(1).
Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S. Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS biology 2012; 10(11).
Peter CJ, Akbarian S. Balancing histone methylation activities in psychiatric disorders. Trends in molecular medicine 2011 Jul; 17(7).
Peter CJ, Evans M, Thayanithy V, Taniguchi-Ishigaki N, Bach I, Kolpak A, Bassell GJ, Rossoll W, Lorson CL, Bao ZZ, Androphy EJ. The COPI vesicle complex binds and moves with survival motor neuron within axons. Human molecular genetics 2011 May; 20(9).
Purbey PK, Jayakumar PC, Patole MS, Galande S. pC6-2/caspase-6 system to purify glutathione-S-transferase-free recombinant fusion proteins expressed in Escherichia coli. Nature protocols 2006; 1(4).
Jayakumar PC, Shouche YS, Patole MS. Functional analysis of Drosophila melanogaster hexokinase Hex-A locus: multiple Initiator-like elements enhance DPE containing promoter activity. Insect molecular biology 2007 Feb; 16(1).
Purbey PK, Jayakumar PC, Deepalakshmi PD, Patole MS, Galande S. GST fusion vector with caspase-6 cleavage site for removal of fusion tag during column purification. BioTechniques 2005 Mar; 38(3).
Jayakumar PC, Musande VV, Shouche YS, Patole MS. The Selenophosphate synthetase gene from Leishmania major. DNA sequence : the journal of DNA sequencing and mapping 2004 Feb; 15(1).