Garabet Yeretssian, PhD
- ASSISTANT PROFESSOR | Medicine, Clinical Immunology
Multi-Disciplinary Training AreasCancer Biology [CAB], Immunology [IMM]
MS, Lebanese University
MS, University of Burgundy
PhD, University of Nantes
Postdoctoral Fellow, McGill University
Our laboratory studies signaling pathways regulating innate immunity and cell death. The research focus is to elucidate the molecular mechanisms and roles of cytosolic pattern recognition receptors of the Nod-like receptor (NLR) family in host defense, chronic inflammation and cancer.
Several established approaches, ranging from genetically modified mouse models to biochemistry and cellular immunology methods, are used in our laboratory to gain insight into the mechanisms that govern host-pathogen interactions, tumor biology and inflammatory-mediated immune disorders.
We are particularly investigating the functions of various apoptosis effectors in infection, inflammatory bowel diseases and colorectal cancer.
Postdoctoral and graduate projects are regularly available.
Saxena M, Yeretssian G. NOD-Like Receptors: Master Regulators of Inflammation and Cancer. Frontiers in Immunology 2014 Jul 14;5:327. doi: 10.3389/fimmu.2014.00327.
Parlato M, Yeretssian G. NOD-like receptors in intestinal homeostasis and epit