Ilse S Daehn, PhD
- ASSISTANT PROFESSOR | Medicine, Nephrology
Research Topics:Cell Biology, Kidney, Mitochondria, Oxidative Stress
Ilse Daehn is an Assistant Professor in the Department of Medicine – Nephrology in Icahn School of Medicine at Mount Sinai since 2013. Her research aims to understand chronic kidney disease development and progression and is currently seeking biomarkers of disease progression in the Institute of Personalized Medicine. Ilse holds a degree in Biotechnology (Honors) from Flinders University of South Australia. She performed a research placement at the Fundacion Jimenez Diaz, Madrid before starting her Doctorate studies at Flinders University of SA, and was awarded her PhD in 2007. She was a postdoctoral fellow at Cancer Research UK, in London and came to NYC to pursue a second postdoctoral fellowship at Mount Sinai.
Ilse is a member of the OAEM Steering Committee and former co-chair of the Postdoc Executive Committee at Mount Sinai. She sits on NYC Tech Connect’s Entrepreneurial Scientist Advisory Panel.
Bachelors, Flinders University
PhD, Flinders University
My research focuses on exploring the complexity of signaling crosstalk between cells in the kidney. Particularly, my work aims to examine molecular mechanisms in the glomerulus that result in kidney disease progression and diabetic nephropathy in order to identify novel glomerular lesion-specific therapeutic targets and biomarkers. I have so far taken innovative approaches to examine the development of glomerular disease and the outcomes from this work have provided a fundamental paradigm shift in our current understanding of chronic kidney disease development.
Blanco-Colio LM, Justo P, Daehn I, Lorz C, Ortiz A, Egido J. Bcl-xL overexpression protects from apoptosis induced by HMG-CoA reductase inhibitors in murine tubular cells. Kidney international 2003 Jul; 64(1).
Gangnuss S, Cowin AJ, Daehn IS, Hatzirodos N, Rothnagel JA, Varelias A, Rayner TE. Regulation of MAPK activation, AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin. The Journal of investigative dermatology 2004 Mar; 122(3).
Daehn IS, Varelias A, Rayner TE. Sodium butyrate induced keratinocyte apoptosis. Apoptosis : an international journal on programmed cell death 2006 Aug; 11(8).
Daehn I, Karran P. Immune effector cells produce lethal DNA damage in cells treated with a thiopurine. Cancer research 2009 Mar; 69(6).
Daehn IS, Varelias A, Rayner TE. T-lymphocyte-induced, Fas-mediated apoptosis is associated with early keratinocyte differentiation. Experimental dermatology 2010 Apr; 19(4).