Yibang Chen, PhD
- ASSISTANT PROFESSOR | Pharmacology and Systems Therapeutics
Dr. Chen is a member of the Iyengar Laboratory within the Department of Pharmacology and Systems Therapeutics.
Fingerle-Rowson G, Kaleswarapu DR, Schlander C, Kabgani N, Brocks T, Reinart N, Busch R, Schutz A, Lue H, Du X, Liu A, Xiong H, Chen Y, Nemajerova A, Hallek M, Bernhagen J, Leng L, Bucala R. A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol 2009 Apr; 29(7): 1922-1932.
Lu TC, Wang Z, Feng X, Chuang P, Fang W, Chen Y, Neves S, Maayan A, Xiong H, Liu Y, Iyengar R, Klotman PE, He JC. Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Mol Cell Biol 2008 Sep; 28(18): 5785-5794.
He HC, Lu TC, Fleet M, Sunamoto M, Husain M, Fang W, Neves S, Chen Y, Shankland S, Iyengar R, Klotman PE. Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. J Am Soc Nephrol 2007 Jan; 18(1): 93-102.
Yoo B, Iyengar R, Chen Y. Functional analysis of the interface regions involved in interactions between the central cytoplasmic loop and the C-terminal tail of adenylyl cyclase. J Biol Chem 2004 Apr 2; 279(14): 13925-13933.
Santore TA, Chen Y, Smith MJ, Iyengar R. Adenovirus-directed expression of Q227L-G alpha(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice. Proc Natl Acad Sci USA 2002 Feb 5; 99(3): 1671-1676.
Buck E, Li J, Chen Y, Weng G, Scarlata S, Iyengar R. Resolution of a signal transfer region from a general binding domain in gbeta for stimulation of phospholipase C-beta2. Science 1999 Feb 26; 283(5406): 1332-1335.
Chen J, Bander JA, Santore TA, Chen Y, Ram PT, Smith MJ, Iyengar R. Expression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesis. Proc Natl Acad Sci USA 1998 Mar 3; 95(5): 2648-2652.
Chen Y, Harry A, Li J, Smith MJ, Bai X, Magnusson R, Pieroni JP, Weng G, Iyengar R. Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation. Proc Natl Acad Sci USA 1997 Dec 9; 94(25): 14100-14104.